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The role of donor-specific HLA antibodies (DSA) following liver transplantation (LTx) is not clearly established. Our aim was to assess the presence of DSA in pediatric LTx recipients. We hypothesized that DSA would be detected (+DSA) in patients with late allograft dysfunction due to de-novo autoimmune hepatitis (d-AIH).Serum was collected at routine clinic visits from 50 pediatric LTx recipients...
The aim of our study was to characterize regulatory immune cells in pediatric liver transplant (pLTx) recipients via immunophenotyping. We hypothesized the analysis would identify a distinct cellular profile of pLTx tolerance.PBMCs were collected during routine visits from pLTx recipients classified as tolerant (TOL, normal liver function off immunosuppression, n=9) or non-tolerant (NON-TOL, ⩾1 late...
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