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Aims To compare effects of heparin and hirudin on biochemical markers of coagulation.Methods and Results Patients (n=395) with unstable angina or myocardial infarction without ST elevation were randomized to a 72-h infusion of one of three regimens: unfractionated heparin (bolus of 5000IU followed by an infusion of 1200IU.h -1 ), low-dose hirudin (HBW 023; 0.2mg.kg -1 bolus...
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