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The recombinant human prolactin was synthesised as an extracellular protein expressed in baculovirus system. The concentration of prolactin in TC-100 medium was approximately 40 mg/l when the conditions of recombinant virus infection were properly chosen. The human prolactin present in culture medium was stable at 4C for several months up to one year. The recombinant product was a survival factor...
Baculoviruses form a largest and most diverse groups of insect-pathogenic viruses. They are safe for plants, vertebrates and - what is particularly important - for mammals and humans. It was established that these insect specific viruses are widespread in nature among economically important insect pests and they may be applied in pest control programe. Numerous field trials demonstrated usefulness...
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