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Both acute sleep loss and chronic sleep loss are common in our society. Insufficient sleep can be detrimental to cognition and health, and disturbed sleep is frequently observed with neurodegenerative pathologies. Conversely, exercise has beneficial effects on cognition and neurocognitive health. Interestingly, many of the same molecules and cellular pathways that alter sleep and are modulated by...
The effects of chronic moderate sleep restriction and exercise training on carcinogenesis were examined in adenomatous polyposis coli multiple intestinal neoplasma (APC Min +/− ) mice, a genetic strain which is predisposed to developing adenomatous polyposis. The mice were randomized to one of four 11week treatments in a 2×2 design involving sleep restriction (by 4h/day) vs. normal sleep and...
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