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The cadherin superfamily of adhesion molecules encompasses over 100 members, which can be subdivided into classical cadherins, desmosomal cadherins, and protocadherins. Many classical cadherins and protocadherins are expressed in the central nervous system (CNS), where they have been implicated in a wide variety of processes. The ∼20 classical cadherins have 5 characteristic cadherin repeats and an...
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