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In Poland, a high level of nitrate and nitrite in food and iodine deficiency have been observed in the last years. The effects of potential goitrogens, namely allylisothiocyanate (SCN-), nitrate (NO3 -) and nitrite (NO2 -) on growth performance, serum hormones (fT4, TSH) and thyroid morphology were investigated in rats. Simultaneously, the potential antigoitrogenic effects of iodine and selenium supplements...
The objectives of the present study were to estimate the effects of increasing levels of the dietary intake of nitrites on: (1) urinary iodine excretion, 2) changes in the morphology of thyroid follicles, and 3) thyroid gland hormonegenesis, in laboratory rats. Effects of nitrites on serum lipoproteins were examined as well. Feeding graded amounts of nitrites to rats resulted in: (1) decreased iodine...
The effect of increasing levels of sodium nitrate on urinary iodine excretion, changes in the morphology of thyroid follicles, and thyroid gland hormonogenesis were studied. In addition, effects of nitrates on serum lipoproteins were examined. Twenty-four, 5-week old, growing male rats of Wistar strain were randomly assigned to four experimental groups (I – 0, II – 500, III – 1500, and IV – 3000 mg...
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