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Aim
Local excision or a wait‐and‐see policy may offer the possibility of organ preservation for locally advanced rectal cancer (LARC) after preoperative chemoradiotherapy (CRT). Identifying associated factors of good responders (GR) with stage ypT0–1N0 would probably influence the selection of potential candidates who were theoretically eligible for organ‐sparing management. This study was to establish...
Objective To evaluate the clinical significance of caspase‐9 mRNA expression and investigate its prognostic value in stage II colorectal cancer.
Method Quantitative real‐time RT–PCR was used to analyse caspase‐9 mRNA expression in cancer tissue and corresponding normal mucosa from 120 patients.
Results Compared with normal mucosa, the expression of caspase‐9 mRNA was found to be downregulated in...
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