Search results for: Allison N.

Items from 1 to 20 out of 169 results

article

A guide to large data sets for population‐based cancer research: Strengths, limitations, and pitfalls

Allison N. Martin, Norine W. Chan, Dillon C. Cheung, Zhi Ven Fong

Cancer > 130 > 22 > 3802 - 3814

With the proliferation of cancer research based on large databases, misalignment of research questions and data set capabilities is inevitable. Nationally maintained databases are appealing to cancer researchers because of the ease of access to large amounts of patient data available for analysis and risk estimation. Data sets that are commonly used in cancer research include the National Cancer Database,...

article

Human keratin matrices promote wound healing by modulating skin cell expression of cytokines and growth factors

Allison N. Ramey‐Ward, Howard P. Walthall, Shakesia Smith, Thomas H. Barrows

Wound Repair and Regeneration > 32 > 3 > 257 - 267

A wide variety of biomaterials has been developed to assist in wound healing, including acellular animal and human‐derived protein matrices. However, millions of patients worldwide still suffer from non‐healing chronic wounds, demonstrating a need for further innovation in wound care. To address this need, a novel biomaterial, the human keratin matrix (HKM), was developed, characterised, and tested...

article

Effectiveness of combined plasma cell therapy and costimulation blockade based desensitization regimen in heart transplant candidates

Nadia Fida, Todd N. Eagar, Allison N. Yun, Alex W. Rogers, more

Clinical Transplantation > 38 > 2 > n/a - n/a

Background Desensitization is one of the strategies to reduce antibodies and facilitate heart transplantation in highly sensitized patients. We describe our center's desensitization experience with combination of plasma cell (PC) depletion therapy (with proteasome inhibitor or daratumumab) and costimulation blockade (with belatacept). Methods We reviewed five highly sensitized patients who underwent...

article

Seasonal drivers of dissolved oxygen across a tidal creek–marsh interface revealed by machine learning

Peter J. Regier, Nicholas D. Ward, Allison N. Myers‐Pigg, Jay Grate, more

Limnology and Oceanography > 68 > 10 > 2359 - 2374

Dissolved oxygen (DO) is a key biogeochemical control in coastal systems, and its concentration and drivers vary markedly through time and space. This makes it difficult to accurately represent coastal DO and associated biogeochemical processes in models, limiting our ability to predict how these systems will respond to global change. We obtained high‐frequency (5‐min) in situ measurements of DO collected...

article

Biologically driven isotopic fractionations in bivalves: from palaeoenvironmental problem to palaeophysiological proxy

Allison N. Curley, Sierra V. Petersen, Stewart M. Edie, Weifu Guo

Biological Reviews > 98 > 4 > 1016 - 1032

Traditional bulk stable isotope (δ¹⁸O and δ¹³C) and clumped isotope (Δ₄₇) records from bivalve shells provide invaluable histories of Earth's local and global climate change. However, biologically driven isotopic fractionations (BioDIFs) can overprint primary environmental signals in the shell. Here, we explore how conventional measurements of δ¹⁸O, δ¹³C, and Δ₄₇ in bivalve shells can be re‐interpreted...

article

An evaluation of preference stability within MSWO preference assessments for children with autism

Isaac J. Melanson, Alexandria L. Thomas, Matthew T. Brodhead, Emma S. Sipila‐Thomas, more

Journal of Applied Behavior Analysis > 56 > 3 > 638 - 655

Previous research has commonly evaluated preference stability over time and across multiple preference assessment administrations. No studies have evaluated shifts in preference across consecutive rounds of a single preference assessment, where rounds refer to each time the experimenter resets the stimulus‐presentation array. The purpose of the present study was to examine the stability of stimulus...

article

Relational Health as a Pathway from Trauma to Flourishing in School Communities

Robert C. Whitaker, Allison N. Herman, Tracy Dearth‐Wesley

Journal of School Health > 93 > 7 > 628 - 637

BACKGROUND Because traumatic life experiences are common, teaching and learning can be difficult without recognizing how trauma can make people feel psychologically unsafe. Safety can be restored through healthy relationships. CONTRIBUTIONS TO THEORY We present a framework for how relational health—the capacity to develop and maintain safe, stable, and nurturing relationships with others—may allow...

article

Rate‐dependent effects of narrative interventions in a longitudinal study of individuals who use alcohol

William H. Craft, Candice L. Dwyer, Devin C. Tomlinson, Yu‐Hua Yeh, more

Alcoholism: Clinical and Experimental Research > 47 > 3 > 566 - 576

Background Delay discounting (DD), the decrease in reward valuation as a function of delay to receipt, is a key process undergirding alcohol use. Narrative interventions, including episodic future thinking (EFT), have decreased delay discounting and demand for alcohol. Rate dependence, the relationship between a baseline rate and change in that rate after an intervention, has been evidenced as a...

article

The influence of increasing atmospheric CO₂, temperature, and vapor pressure deficit on seawater‐induced tree mortality

Weibin Li, Nate G. McDowell, Hongxia Zhang, Wenzhi Wang, more

New Phytologist > 235 > 5 > 1767 - 1779

Increasing seawater exposure is killing coastal trees globally, with expectations of accelerating mortality with rising sea levels. However, the impact of concomitant changes in atmospheric CO₂ concentration, temperature, and vapor pressure deficit (VPD) on seawater‐induced tree mortality is uncertain. We examined the mechanisms of seawater‐induced mortality under varying climate scenarios using...

article

Anhydrous Nucleic Acid Nanoparticles for Storage and Handling at Broad Range of Temperatures

Allison N. Tran, Morgan Chandler, Justin Halman, Damian Beasock, more

Small > 18 > 13 > n/a - n/a

Recent advances in nanotechnology now allow for the methodical implementation of therapeutic nucleic acids (TNAs) into modular nucleic acid nanoparticles (NANPs) with tunable physicochemical properties which can match the desired biological effects, provide uniformity, and regulate the delivery of multiple TNAs for combinatorial therapy. Despite the potential of novel NANPs, the maintenance of their...

article

Changes in OGTT‐derived biomarkers in response to lifestyle intervention among Latino adolescents with obesity

Armando Peña, Joon Young Kim, Jessica A. Reyes, Kiley B. Vander Wyst, more

Pediatric Obesity > 17 > 4 > n/a - n/a

Background Glucose concentrations during an oral glucose tolerance test (OGTT) have been used as biomarkers to differentiate type 2 diabetes risk phenotypes. No studies have examined changes in OGTT‐glucose phenotypes following lifestyle intervention among high‐risk youth. Objective To examine changes in OGTT‐glucose phenotypes following lifestyle intervention and to explore differences in insulin...

article

Intrinsic reactivity of [OUCH]⁺: Apparent synthesis of [OUS]⁺ by reaction with CS₂

Luke J. Metzler, Christopher T. Farmen, Allison N. Fry, Mark P. Seibert, more

Rapid Communications in Mass Spectrometry > 36 > 8 > n/a - n/a

Rationale Building on our report that collision‐induced dissociation (CID) can be used to create the highly reactive U‐alkylidyne species [O=U≡CH]⁺, our goal was to determine whether the species could be as an intermediate for synthesis of [OUS]⁺ by reaction with carbon disulfide (CS₂). Methods Cationic uranyl‐propiolate precursor ions were generated by electrospray ionization, and multiple‐stage...

article

Differential investment in visual and olfactory brain regions is linked to the sensory needs of a wasp social parasite and its host

Allison N. Rozanski, Alessandro Cini, Taylor E. Lopreto, Kristine M. Gandia, more

Journal of Comparative Neurology > 530 > 4 > 756 - 767

Obligate insect social parasites evolve traits to effectively locate and then exploit their hosts, whereas hosts have complex social behavioral repertoires, which include sensory recognition to reject potential conspecific intruders and heterospecific parasites. While social parasites and host behaviors have been studied extensively, less is known about how their sensory systems function to meet their...

article

Programmable Mechanically Active Hydrogel‐Based Materials

Yixiao Dong, Allison N. Ramey‐Ward, Khalid Salaita

Advanced Materials > 33 > 46 > n/a - n/a

Programmable mechanically active materials (MAMs) are defined as materials that can sense and transduce external stimuli into mechanical outputs or conversely that can detect mechanical stimuli and respond through an optical change or other change in the appearance of the material. Programmable MAMs are a subset of responsive materials and offer potential in next generation robotics and smart systems...

article

Teaching choice‐making within activity schedules to children with autism

Nicole M. Deel, Matthew T. Brodhead, Jessica S. Akers, Allison N. White, more

Behavioral Interventions > 36 > 4 > 731 - 744

Though the value of choice‐making opportunities in behavioral interventions is well established, specific demonstrations of its applications are limited. In this study, we first taught participants to independently complete two types of activity schedules: a choice activity schedule (i.e., one that allowed the participants to choose the sequence of activities) and a no choice activity schedule (i...

article

Diabetes distress and glycaemic control in young adults with type 1 diabetes: Associations by use of insulin pumps and continuous glucose monitors

Kathryn E. Nagel, Tracy Dearth‐Wesley, Allison N. Herman, Hannah G. Smith, more

Diabetic Medicine > 38 > 11 > n/a - n/a

Aims We determined whether high diabetes distress (DD) in young adults with type 1 diabetes was associated with higher glycated haemoglobin (HbA_1c) levels and whether this association was similar among those who were and were not using diabetes devices (insulin pumps and/or continuous glucose monitors [CGMs]). Methods In 2017, an online survey was completed by 423 of 743 (57%) young adults (19–31 years)...

article

Validated quantitative needs assessment differences in the management of children with central nervous system cancer between Brazil, an upper middle‐income country, and the United States of America, a high income country

Allison N. Fischer, Roberto Roecker, Nasjla Saba da Silva, Sergio Cavalheiro, more

Pediatric Blood & Cancer > 68 > 6 > n/a - n/a

Background Pediatric cancer cure rates differ among high‐income countries (HIC) and upper middle‐income countries (UMIC). We have compared individual capacities of two major referral pediatric centers from a HIC and an UMIC caring for children with central nervous system (CNS) cancer. Methods A quantitative needs assessment questionnaire and key informant interviews, distributed in March of 2017,...

article

A methodological review of preference displacement research

Allison N. White, Isaac J. Melanson, Emma S. Sipila‐Thomas, Matthew T. Brodhead

Behavioral Interventions > 36 > 1 > 171 - 194

The purpose of this review was to identify and compare methodological components of preference displacement research and outcomes. We coded, categorized, and defined patterns of preference displacement for a total of 133 participants across 10 studies. We found that patterns of displacement differed within and across studies, and over 46% of participants did not engage in patterns of displacement...

article

Pharmacokinetic and pharmacodynamic analyses of cocaine and its metabolites in behaviorally divergent inbred mouse strains

Jing Zhu, Ryan J. Beechinor, Trey Thompson, Allison N. Schorzman, more

Genes, Brain and Behavior > 20 > 2 > n/a - n/a

Cocaine (COC) is a psychostimulant with a high potential for abuse and addiction. Risk for COC use disorder is driven, in part, by genetic factors. Animal models of addiction‐relevant behaviors have proven useful for studying both genetic and nongenetic contributions to drug response. In a previous study, we examined initial locomotor sensitivity to COC in genetically diverse inbred mouse strains...

article

A replication of preference displacement research in children with autism spectrum disorder

Emma S. Sipila‐Thomas, Alexa J. Foote, Allison N. White, Isaac J. Melanson, more

Journal of Applied Behavior Analysis > 54 > 1 > 403 - 416

The purpose of this paper was to replicate previous research on preference displacement with edible and leisure stimuli. In the present study, the experimenters evaluated preference displacement in 25 children with autism spectrum disorder using combined multiple stimulus without replacement preference assessments that consisted of highly preferred edible and leisure stimuli. In addition, the experimenters...

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INFONA - science communication portal

Search results for: Allison N.

A guide to large data sets for population‐based cancer research: Strengths, limitations, and pitfalls

Human keratin matrices promote wound healing by modulating skin cell expression of cytokines and growth factors

Effectiveness of combined plasma cell therapy and costimulation blockade based desensitization regimen in heart transplant candidates

Seasonal drivers of dissolved oxygen across a tidal creek–marsh interface revealed by machine learning

Biologically driven isotopic fractionations in bivalves: from palaeoenvironmental problem to palaeophysiological proxy

An evaluation of preference stability within MSWO preference assessments for children with autism

Relational Health as a Pathway from Trauma to Flourishing in School Communities

Rate‐dependent effects of narrative interventions in a longitudinal study of individuals who use alcohol

The influence of increasing atmospheric CO₂, temperature, and vapor pressure deficit on seawater‐induced tree mortality

Anhydrous Nucleic Acid Nanoparticles for Storage and Handling at Broad Range of Temperatures

Changes in OGTT‐derived biomarkers in response to lifestyle intervention among Latino adolescents with obesity

Intrinsic reactivity of [OUCH]⁺: Apparent synthesis of [OUS]⁺ by reaction with CS₂

Differential investment in visual and olfactory brain regions is linked to the sensory needs of a wasp social parasite and its host

Programmable Mechanically Active Hydrogel‐Based Materials

Teaching choice‐making within activity schedules to children with autism

Diabetes distress and glycaemic control in young adults with type 1 diabetes: Associations by use of insulin pumps and continuous glucose monitors

Validated quantitative needs assessment differences in the management of children with central nervous system cancer between Brazil, an upper middle‐income country, and the United States of America, a high income country

A methodological review of preference displacement research

Pharmacokinetic and pharmacodynamic analyses of cocaine and its metabolites in behaviorally divergent inbred mouse strains

A replication of preference displacement research in children with autism spectrum disorder

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