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The review describes current diagnostic techniques used for TSEs diagnosis with emphasis on BSE and scrapie in sheep. The clinical signs and their reliability are presented along with the review of laboratory tests. Special emphasis has been placed on the diagnostic reliability of clinical signs including their sensitivity and specificity. Histopatological examination for BSE is discussed with guidelines...
The review describes the European Commission’s report concerning the evaluation of tests used for diagnosis of transmissible spongiform encephalopathy in bovines. Four kits already available on the market or in the final stage of being released onto market were tested. The following parameters were examined: specificity, sensitivity and the ability to detect small quantities of PrP as well as reproducibility...
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