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Our study identified Heligmosomoides polygyrus antigen factors with potential activity for regulation of T‐cell proliferation and surviving of CD4+CD25−, CD4+CD25hi and CD3+CD8+ cell populations. The antiapoptotic activity of antigenic fractions separated by HPLC was evaluated in vitro after exposure of cells to DEX and rTNF‐α. Different populations of cells responded to antigen fractions in distinct...
Primary exposure of mice to the nematode Heligmosomoides polygyrus infection reduces inflammation in an experimental model of colitis. The aim of the present investigation was to evaluate whether the reduced inflammation provoked by H. polygyrus L4 larvae in BALB/c mice treated with dextran sulphate sodium is associated with changed expression of opioids in the small intestine and colon. Colitis was...
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