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Anandamide (AEA) and 2-arachidonyl glycerol (2-AG), endogenous ligands for the CB1 and CB2 cannabinoid receptors, are referred to as endocannabinoids because they mimic the actions of delta 9 -tetrahydrocannabinol (Δ 9 -THC), a plant-derived cannabinoid. The processes by which AEA and 2-AG are biosynthesized, released, taken up by cells and hydrolyzed have been of much interest as...
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