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The aim of the study was to determine whether monobromobenzene (BB) and hexabromobenzene (HBB) administered repeatedly (for 28 days) to female rats resulted in disturbances of heme synthesis. 5-Aminolevulinate dehydratase (ALA-D) and 5-aminolevulinate synthase (ALA-S) activities were slightly changed and the concentration of glutathione increased. The excretion of 5-aminolevulinic acid (ALA-U) in...
The aim of this study was to compare liver impairment in acute intoxication of mice with bromobenzene (BB), tribromobenzenes (1,2,4-triBB, 1,3,5-triBB), 1,2,4,5-tetrabromobenzene (1,2,4,5-tetraBB) and hexabromobenzene (HBB). The data were compared with the results for dibromobenzenes published by Szymanska et. al (J. Appl. Toxicol. 16, 35-41, 1996). Male Balb'c mice were administered the compounds...
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