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EAE (Experimental Allergic Encephalomyelitis) is the animal model of Multiple Sclerosis, an autoimmune and neurodegenerative human disease. Proposed method for autoimmune diseases treatment is to evoke oral tolerance, which is lack of response to fed antigen. Our previous experiments showed that pig spinal cord hydrolysate, which is source of myelin antigens is able to evoke oral tolerance in EAE...
The aim of this work was to evaluate the histopathological changes in dog adrenals with a special attention to cortical-cell lipidosis. The routine histopathological examinations were performed in adrenals, which were obtained post mortem from 50 dogs of both sexes, 1-22 years old. The research revealed the presence of lipidosis in the cells of zona reticulosa, and/or proliferation of cortical cells...
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