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Aims
To characterise the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of single ascending doses of oxathridine, a first‐in‐class histamine‐3 receptor partialagonist, in healthy male volunteers.
Methods
A randomised, double‐blind, placebo‐controlled study including the NeuroCart, consisting of a battery of drug sensitive neurophysiological tests, was performed. Oxathridine...