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The efficiency of transdermal drug delivery (TDD) is often undermined by stratum corneum of skin. In this paper, a novel design and fabricating process was developed to coat microneedles (MNs). Testing results of facture strength of the MNs demonstrated that the Ni coated microneedle can meet the mechanical requirement for practical TDD applications. Dip-coating experiment demonstrated that it was...
The key issue in the research of microneedles is how to fabricate microneedles with low cost and good quality. This paper presents a process for fabrication of cone out-of-plane Ni microneedles and characterizes their properties. The fabrication process consisted of inclined rotational MASK and wafer exposure, fine pattern transfer of polydimethylsiloxane (PDMS) and electroplating. The efficiency...
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