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We describe a new, single pot, aqueous phase method for synthesizing water soluble gold nanoparticles (AuNPs) over a size range of 15–130nm. Poly(ethylene glycol)-appended thioctic acid ligands were used to control the growth rates and stabilize the AuNPs. Critical factors that enable the controlled growth of the AuNPs over this size range include the pH, the choice of reducing agent, the reaction...
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