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Objective To explore the effects of Kaixin Powder (开心散, KXP) on melatonin receptor (MR) expression and 125I-Mel binding affinity in a depression rat model. Methods Seventy-two male Wistar rats were divided into six groups: a blank control group, model group, ramelteon group, KXP high-dosage group (HKXP), medium-dosage group (MKXP) and low-dosage group (LKXP). To establish the depression model, all...
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