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Although widely regarded as attractive drug targets, less than a tenth of known ion channels are currently commercially exploited as therapeutic targets. Historically, drug discovery efforts on ion channel targets have been encumbered by a lack of molecular and structural information, sub-optimal screening technologies and a paucity of discriminating pharmacological tools. Although challenges remain,...
This article has been retracted by the editors of Drug Discovery Today because of serious errors introduced during its production. It will be available shortly in the second issue of 2005 in the correct form.We stress that these errors are in no way the fault of the authors and we apologise sincerely to our readers and the authors for the inconvenience caused.
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