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Laboratory mice are most commonly killed with carbon dioxide (CO 2 ), a gas they may find aversive. The aim of this study was to use approach-avoidance testing to record mouse responses to CO 2 and to four alternatives: argon, carbon monoxide (CO), and the inhalant anaesthetics halothane and isoflurane. Mice were trained to enter the bottom cage of a two-cage apparatus for a reward...
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