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Mn 2+ is a minor nutrient, but is essential for numerous enzymatic activities and thus, for many cellular functions. However, its physiological roles and toxicity remain to be elucidated. In this study, we assessed the pharmacological potential and toxicity of Mn 2+ in the immune system by examining the effects of Mn 2+ on interleukin-2 (IL-2) production by Jurkat T-cells....
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