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In article number 2005550, Shoji Takeuchi and co‐workers present a parallel lipid bilayer array with integrating series resistors for sensitive and resilient detection of toxin pore formation, illustrated by electrical signatures. This array will help in understanding toxic activity and development of diagnosis, treatment, and control of bacterial infections in medicine.
An artificial cell membrane is applied to study the pore formation mechanisms of bacterial pore‐forming toxins for therapeutic applications. Electrical monitoring of ionic current across the membrane provides information on the pore formation process of toxins at the single pore level, as well as the pore characteristics such as dimensions and ionic selectivity. However, the efficiency of pore formation...
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