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The “Switching – On” complexes, indolium derivatives bound with nuclear acids, were used as fluorescence probes to recognize the endonuclease and monitor the enzyme activities. Three probes, H1, L1 and N1, weakly emitted in aqueous buffer, exhibited strong red emissions when they bound into DNA or RNA. For H1-RNA or L1-RNA, the fluorescence was sensitively quenched by endoribonuclease, RNase A. The...
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