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The adsorption of a therapeutic enzyme to self-assembled monolayers (SAMs) of different functionalities (X=CH 3 -, OH- and COOH-) was evaluated as a function of solution pH. Radiolabelling studies showed that the enzyme has higher affinity for hydrophobic surfaces than for hydrophilic surfaces, and that the highest adsorption was obtained at the more acidic pH values (4.5 and 5.5), despite...
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