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We report the observation and analysis of the low frequency vibrational modes of green fluorescent proteins (GFPs). Our study exploits the surface enhanced Raman scattering technique, which allowed the analysis of the vibrational modes of the proteins down to 300 cm -1 . Here we present results on two GFP mutants, namely S65T/F64L GFP (EGFP) and S65T/F64L/T203Y GFP (E 2 GFP)....
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