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Background
Our previous report has shown that the flavonoid 2′‐hydroxyflavanone (2′‐HF) showed inhibition of androgen receptor (AR) activity against androgen‐sensitive prostate cancer (PCa) cells, LNCaP, and exhibited antitumor effects against androgen‐insensitive PCa cells, PC‐3, and DU145. In the present study, we prepared a derivative of 2′‐HF, 16MS7F1924, and confirmed the effects of this derivative...
Background
Coffee inhibits the progression of prostate cancer; however, the direct mechanism through which coffee acts on prostate cancer cells remains unclear. This study aimed to identify the key compounds of coffee that possess anti‐cancer effects and to investigate their mechanisms of action.
Methods
The anti‐proliferation and anti‐migration effects of six potentially active types of coffee...
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