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Objectives The aim was to examine the biological activity of 5‐methoxytryptamine derivatives at the 5‐hydroxytryptamine (5‐HT)4 receptor to explore the effect of substitution on the aliphatic amine of the 5‐methoxyamine scaffold.
Methods Three compounds were tested for affinity at the 5‐HT4 receptor by radioligand binding and functional activity using guinea‐pig ileum and human colon circular muscle...
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