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The cocaine analog 3β-(4-iodophenyl)tropane-2β-carboxylic acid methyl ester (RTI-55 or βCIT) has a higher affinity for the dopamine transporter and may be potentially useful in interfering with cocaine's actions in brain. However, imaging studies have demonstrated displacement of tracer doses of [ 123 I]RTI-55 by a subsequent dose of cocaine. Similar displacement of pharmacological...
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