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Purpose A polysaccharide-flavonoid conjugate was developend and proposed for the treatment of pancreatic ductal adenocarcinoma (PDAC). Methods The conjugate was synthesized by free radical grafting reaction between catechin and dextran. The chemical characterization of the conjugate was obtained by UV-Vis, 1H-NMR, FT-IR and GPC analyses, while the functionalization degree was determined by the Folin-Ciocalteu...
In the present study, catechin–alginate and catechin–inulin conjugates were obtained by adopting free radical-induced grafting procedure. In the aim to synthesize the antioxidant–polysaccharide conjugates, ascorbic acid/hydrogen peroxide redox pair was employed as water-soluble and biocompatible initiator system. The insertion of catechin onto the polymeric backbones was verified by performing FT-IR,...
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