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An overabundant discharge of inflammatory mediators plays a significant role in intestinal injury throughout the early stages of critical burns. The present study aims to explore the outcome of 200mM hypertonic saline (HS) resuscitation on the intestinal injury of critically burned rats.Fifty-six Sprague-Dawley rats were randomized into three groups: sham group (group A), burn plus lactated Ringer’s...
The healing of wounds has always provided challenges for the medical community whether chronic or acute. Modern and traditional medicine has proved that herbal medicine shown superiority over chemical drugs. Herein, we report an Entada phaseoloides (L.) Merr. extract with a total tannin content of 76.18% showed wound-healing promoting effect in rat model. We found significantly accelerated wound closure...
Challenges persist in the reconstruction of the ankle and the foot with exposed tendons, joints, and bones as a result of severe burns and trauma. In flap elevation involving the sensitive superficial nerve, the local nerve was always sacrificed to obtain an anesthetic donor site; however, such a procedure introduced the possibility of painful neuromas. In this study, we present a desired clinical...
Puerarin, the main isoflavone glycoside extracted from the root of Pueraria lobata, is widely prescribed for patients with cardiovascular disorders in China. This study investigates the effect of puerarin on severe burn-induced acute myocardial injury in rats and its underlying mechanisms.Healthy adult Wistar rats were divided into three groups: (1) sham group, sham burn treatment; (2) burn group,...
Despite the fact that early excision and grafting have significantly improved burn outcomes, the management of severely burned patients whose burn size exceeds 70% total body surface area (TBSA) still represents a big challenge for burn surgeons all over the world. During the period of 1997–2010 at our centre, aggressive excision and microskin autografting were performed in 63 severely burned patients...
The Chinese peasants in the middle of Anhui Province and north of Dabieshan Mountain are accustomed to using industrial alcohol to kindle honeycomb briquettes in their household coal stoves. Pouring alcohol into the stove often results in flame burns when the honeycomb briquettes inside are not completely extinguished. The purpose of this study is to describe the unique cause and clinical characteristics...
The aim of this retrospective, comparative study was to analyse the management of extensive burns so as to decrease morbidity and mortality. Over 1987–1996, 24 people with burns >80% of total body surface area and >50% full-thickness burn were admitted to the burn unit of Anhui Medical University Hospital (group A); 30 similar admissions over 1997–2006 formed group B. No significant difference...
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