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The calcium responses to serotonin and thrombin, as assessed using the fluorescent indicator Fura-2, have been investigated in platelets taken from 59 non-smokers and 17 smokers. The peak responses above baseline, calculated either as fluorescence ratios or calibrated calcium concentrations, were in the order of magnitude thrombin 520 mU/ml>thrombin 52 mU/ml serotonin 1 μmol/l~serotonin 100 μmol/l...
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