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J. Neurochem. (2010) 114, 1097–1106.
AbstractNeuroendocrine regulatory peptide (NERP)‐1 and NERP‐2 are biologically active peptides recently discovered by peptidomic analysis. NERPs are processed out from the 594‐residue VGF protein which contains many prohormone convertase cleavage motifs. VGF‐deficient mice exhibit a hypermetabolic and infertile phenotype, for which VGF protein‐derived peptides...
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