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Bone morphogenetic protein‐2 (BMP‐2) has a crucial role in the development of cardiogenesis, and is used in inducing bone marrow mesenchymal stem cells (BMMSCs) to differentiate into cardiomyocytes. We have examined a combination of BMP‐2 and 5‐azacytidine (5‐AZA) in inducing these differentiation effects. BMMSCs were collected and purified from bone marrow of 4‐week‐old Sprague‐Dawley (SD) rats by...
Adult bone marrow mesenchymal stem cells (MSCs) can differentiate into several types of mesenchymal cells, including osteocytes, chondrocytes, and adipocytes, but can also differentiate into non-mesenchymal cells, such as neural cells, under appropriate experimental conditions. Until now, many protocols for inducing neuro-differentiation in MSCs in vitro have been reported. But due to the differences...
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