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We design and implement Mars, a MapReduce framework, on graphics processors (GPUs). MapReduce is a distributed programming framework originally proposed by Google for the ease of development of web search applications on a large number of commodity CPUs. Compared with CPUs, GPUs have an order of magnitude higher computation power and memory bandwidth, but are harder to program since their architectures...
Sequence alignment is a fundamental task for computational genomics research. We develop G-Aligner, which adopts the GPU as a hardware accelerator to speed up the sequence alignment process. A leading CPU-based alignment tool is based on the Bi-BWT index; however, a direct implementation of this algorithm on the GPU cannot fully utilize the hardware power due to its irregular algorithmic structure...
We have developed GSNP, a software package with GPU acceleration, for single-nucleotide polymorphism detection on DNA sequences generated from second-generation sequencing equipment. Compared with SOAPsnp, a popular, high-performance CPU-based SNP detection tool, GSNP has several distinguishing features: First, we design a sparse data representation format to reduce memory access as well as branch...
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