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The recent ban of titanium dioxide (TiO2) as a food additive (E171) in France intensified the controversy on safety of foodborne‐TiO2 nanoparticles (NPs). This study determines the biological effects of TiO2 NPs and TiO2 (E171) in obese and non‐obese mice. Oral consumption (0.1 wt% in diet for 8 weeks) of TiO2 (E171, 112 nm) and TiO2 NPs (33 nm) does not cause severe toxicity in mice, but significantly...
In article number 2001858, Hang Xiao and co‐workers study how oral consumption of food additive TiO2 (E171, 112 nm) or TiO2 nanoparticles (NPs) (33 nm) leads to a series of adverse effects in mice, such as gut microbiota dysbiosis, colonic inflammation, and altered hepatic and colonic proteome. Importantly, TiO2 NPs produce stronger adverse effects than TiO2 (E171), and obese mice are more susceptible...
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