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Phototherapy is a promising treatment method for cancer therapy. However, the various factors have greatly restricted phototherapy development, including the poor accumulation of photosensitizer in tumor, hypoxia in solid tumor tissue and systemic phototoxicity. Herein, a mitochondrial‐targeted multifunctional dye‐anchored manganese oxide nanoparticle (IR808@MnO NP) is developed for enhancing phototherapy...
In article number 1605928, Gang Liu and co‐workers from Xiamen University develop a new generation of phototheranostic agents using a tumor‐environment‐triggered co‐assembly strategy. MnO2 nanosheets serve as a highly effective photosensitizer carrier and in situ oxygen and nanotheranostic generator, with promising properties for trimodal MR‐/fluorescence‐/photoacoustic‐imaging‐guided phototherapy...
The efficacy of photosensitizers in cancer phototherapy is often limited by photobleaching, low tumor selectivity, and tumor hypoxia. Assembling photosensitizers into nanostructures can improve photodynamic therapy efficacy and the safety profile of photosensitizers. Herein by employing supramolecular assembly, enhanced theranostic capability of Mn2+‐assisted assembly of a photosensitizer (sinoporphyrin...
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