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P450 reporter gene system (RGS) utilizes a human hepatoma cell line stably transfected with a plasmid containing firefly luciferase linked to human CYP1A1 promoter sequences. Luciferase expression in these cells is used to detect and quantify compounds that activate the Ah receptor (AhR) and induce CYP1A1. In this study, concentration-response curves were used to determine the relative potencies and...
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