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Objective To investigate homozygous deletions and mutations in the CDKN2A gene (p16INK4a and p14ARF gene) in hydatidiform moles. Methods A total of 38 hydatidiform mole samples and 30 villi samples were examined for homozygous deletions in the CDKN2A gene by PCR and for mutations by DHPLC. Results i) Among 38 hydatidiform mole samples, homozygous deletions in the p16INK4a exon 1 were identified...
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