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RationaleControversy exists over the optimal dose of intravenous (iv) recombinant tissue plasminogen activator (rt‐PA) and degree of blood pressure (BP) control in acute ischaemic stroke (AIS). Asian studies suggest low‐dose (0·6 mg/kg) is more efficacious than standard‐dose (0·9 mg/kg) iv rt‐PA, and guidelines recommend reducing systolic BP to <185 mmHg before and <180 mmHg after use of iv...
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