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Exposure to intense noise induces apoptosis in hair cells in the cochlea. To identify the molecular changes associated with noise-induced apoptosis, we used quantitative real-time PCR to evaluate the changes in 84 apoptosis-related genes in cochlear samples from the sensory epithelium and lateral wall. Sprague–Dawley rats exposed to a continuous noise at 115 dB SPL for 2 h. The exposure caused a 40–60...
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