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Modeling G‐Protein Coupled Receptors (GPCRs) is an emergent field of research, since utility of high‐quality models in receptor structure‐based strategies might facilitate the discovery of interesting drug candidates. The findings from a quantitative analysis of eighteen resolved structures of rhodopsin family “A” receptors crystallized with antagonists and 153 pairs of structures are described. A...
G protein‐coupled receptors (GPCRs) are a super‐family of membrane proteins that attract great pharmaceutical interest due to their involvement in almost every physiological activity, including extracellular stimuli, neurotransmission, and hormone regulation. Currently, structural information on many GPCRs is mainly obtained by the techniques of computer modelling in general and by homology modelling...
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