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High‐dose infusion of IgG (IVIG) is used to treat autoimmune and inflammatory diseases, including Kawasaki disease (KD). Although the immunomodulatory effects of IVIG on blood cells such as macrophages have been well studied, its effects on tissue cells remain unclear. Here, we show that high‐dose IgG specifically and completely inhibited TNF‐α‐induced, but not IL‐1β‐induced, secretion of proinflammatory...
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