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Ulcerative colitis (UC) is a chronic inflammatory bowel disease with mucosal inflammation and ulceration of the colon. There seems to be no single etiological factor responsible for the onset of the disease. Autoimmunity has been emphasized in the pathogenesis of UC. Perinuclear anti-neutrophil cytoplasmic antibodies (pANCA) are common in UC, and recently two major species of proteins immunoreactive...
Extraintestinal manifestations in patients withinflammatory bowel disease (IBD) are quite common (about25%) and careful clinical observation and statisticalanalysis during the last five decades have demonstrated that in colitis-associatedextraintestinal complications, the organs most commonlyinvolved are the biliary tract, joints, skin, and eyes.However, almost all organs can be involved in IBD. Some...
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