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The purpose of this study was to evaluate the wound‐healing effects of a novel benzalkonium chloride (BC)‐loaded hydrocolloid wound dressing (HCD). A BC‐loaded HCD was prepared with various constituents using a hot melting method, and its mechanical properties and antimicrobial activities were assessed. The in vivo wound healings of the BC‐loaded HCD in various would models were evaluated in rats...
Silicone‐based formulations are extensively used for the management of hypertrophic scars. Although the exact mechanism of action is still unknown, it has been postulated that some occlusion and hydration of the stratum corneum with subsequent cytokine‐mediated signaling from keratinocytes to dermal fibroblasts is involved in its antiscarring effects. In this study, the effectiveness of silicone‐based...
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