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Squalene-hopene cyclases (SHC; EC 5.4.99.17) catalyze the cyclization of triterpenoids via cationic intermediates in one of the most complex reactions known in biochemistry. In this study, we report the functional expression of a novel SHC from the ethanol producing bacterium Zymomonas mobilis (ZmoSHC1; YP_163283.1). Biochemical characterization of ZmoSHC1 uncovered unique substrate activity patterns...
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