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Guluronate oligomers have been shown to modify the gastrointestinal mucus barrier and improve nanoparticle penetration. Here we investigate the effect of guluronate oligomers on nanoparticle mobility in saliva, a central extracellular barrier in the oral cavity. Guluronate oligomers reduced nanoparticle aggregation in saliva and improved nanoparticle mobility over and above that which would be expected...
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