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Myocardial ischemia‐reperfusion (I/R) injury is unavoidable during cardioplegic arrest and open‐heart surgery. Danshen is one of the most popular traditional herbal medicines in China, which has entered the Food and Drug Administration‐approved phase III clinical trial. This study was aimed to develop a human‐induced pluripotent stem cell‐derived cardiomyocytes (hiPSC‐CMs) model to mimic I/R injury...
Embryonic stem cells (ESCs) hold great promises for treating and studying numerous devastating diseases. The molecular basis of their potential is not completely understood. Large noncoding RNAs (lncRNAs) are an important class of gene regulators that play essential roles in a variety of physiologic and pathologic processes. Dozens of lncRNAs are now identified to control ESC self-renewal and differentiation...
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