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To select normal fertilized diploid blastocysts in patients who had only monopronucleated (1PN) embryos for transfer.Experimental study.University-affiliated center.Couples who were undergoing intracytoplasmic sperm injection treatment and had 1PN blastocysts.In a preliminary test, limited cells of parthenogenetic human embryonic stem cells (phESCs) and normal fertilized blastocysts were analyzed...
In IVF cycles using a GnRH agonist down-regulation short protocol, when the concentration of P on day 4 of stimulation was >3 ng/mL, patients experienced a significantly reduced implantation rate (14.1%), pregnancy rate (24.6%), and ongoing pregnancy rate (20.0%), with an elevated early miscarriage rate (18.8%).
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