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We have studied the hydration and dynamics of RNA C2'-OH in a DNA.RNA hybrid chimeric duplex [d(CGC)r(aaa)d(TTTGCG)] 2 . Long-lived water molecules with correlation time τ c larger than 0.3 ns were found close to the RNA adenine H2 and H1' protons in the hybrid segment. A possible long-lived water molecule was also detected close to the methyl group of 7T in the RNA-DNA junction but...
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