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Arrestins are proteins that arrest the activity of G protein-coupled receptors (GPCRs). While it is well established that normal inactivation of photoexcited rhodopsin, the GPCR of rod phototransduction, requires arrestin (Arr1), it has been controversial whether the same requirement holds for cone opsin inactivation. Mouse cone photoreceptors express two distinct visual arrestins: Arr1 and Arr4....
We point out that inliers adversely affect performance of the spatial median and its generalization due to Gentleman. They are most deleterious in the case of the median itself, and in the important setting of two dimensions. There, the second term in a stochastic expansion of the median has a component with a Cauchy limiting distribution, and does not have any finite moments. This term is substantially...
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