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Focal ischemic stroke (FIS) is a leading cause of human death. Glial scar formation largely caused by reactive astrogliosis in peri‐infarct region (PIR) is the hallmark of FIS. Glial cell‐derived neurotrophic factor (GDNF) was originally isolated from a rat glioma cell‐line supernatant and is a potent survival neurotrophic factor. Here, using CreERT2–LoxP recombination technology, we generated inducible...
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